Selected Publications
Kokubu, M., Nishio, M. Ribar, T.J., Anderson, K.A., West, A.E., and Means, A.R. (2009.) BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV. J. Neurosci 29: 8901-8913.

Hong EJ, West AE, Greenberg ME. Transcriptional control of cognitive development.
Curr Opin Neurobiol. 2005 Feb;15(1):21-8. Review.
PMID: 15721740 [PubMed - indexed for MEDLINE]

Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME.
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2.
Science. 2003 Oct 31;302(5646):885-9.
PMID: 14593183 [PubMed - indexed for MEDLINE]

Chen WG, West AE, Tao X, Corfas G, Szentirmay MN, Sawadogo M, Vinson C, Greenberg ME.
Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.
J Neurosci. 2003 Apr 1;23(7):2572-81.
PMID: 12684442 [PubMed - indexed for MEDLINE]

West AE, Griffith EC, Greenberg ME. Regulation of transcription factors by neuronal activity.
Nat Rev Neurosci. 2002 Dec;3(12):921-31. Review. No abstract available.
PMID: 12461549 [PubMed - indexed for MEDLINE]

Tao X, West AE, Chen WG, Corfas G, Greenberg ME.
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF.
Neuron. 2002 Jan 31;33(3):383-95.
PMID: 11832226 [PubMed - indexed for MEDLINE]

By studying the expression and activity of transcriptional regulators in the nervous system we hope to understand how these proteins modulate long-lasting neuronal responses to the environment. Shown above, the transcriptional repressor MeCP2 (red), the GABAergic interneuron marker parvalbumin (green) and nuclei (blue) in the hippocampus of an adult mouse.